Cortisol
Cortisol is a potent glucocorticoid produced by our adrenal glands. It is manufactured from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH). This activity is regulated by corticotropin releasing factor (CRF).
ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Cortisol production has an ACTH-dependent circadian rhythm with peak levels in the early morning and a nadir at night. The factor controlling this rhythm is not completely defined and can be disrupted by a number of physical and psychological conditions. ACTH and cortisol are secreted independent of circadian rhythm in response to physical and psychological stress.
Elevated cortisol levels and lack of diurnal variation have been identified with Cushing’s disease (ACTH hypersecretion). Elevated circulating cortisol levels have also been identified in patients with adrenal tumors. Low cortisol levels are found in primary adrenal insufficiency (e.g. adrenal hypoplasia, Addison’s disease) and in ACTH deficiency. Due to the normal circadian variation in cortisol levels, distinguishing normal from abnormally low cortisol levels can be difficult, therefore several daily collections are recommended.
Cortisol levels in saliva reflect the active unbound compound. Cortisol is measured in ng/ml.
Cortisol Ranges for Women and Men using saliva testing:
- A.M. 1.0 - 8.0
- P.M. 0.1 - 1.0
Saliva samples are collected at home and conveniently travel through the US mail at room temperature. Hormone results are available to the consumer and/or medical provider in three to five days. Simple and painless saliva collection eliminates drawing blood and permits the specimen to be collected in the early morning when hormone results are most meaningful. Dr. John Lee believe3s this is the most accurate way to test hormones.
Benefits of Cortislim:
- Promotes Weight Loss
- Reduce Stress
- Suppresses your appetite
- Ephedra free
- Increases energy
Recommended Dosage:
CortiSlim is formulated to be taken with
breakfast and lunch – so you only need
to take it twice each day.
Precautions:
- Keep out of the reach of
children
- Always consult with your
physician before beginning any
weight loss program
- As with any natural product,
there will be a range of effects
experienced by users. CortiSlim™
does not contain ephedrine
- Each of the ingredients in
CortiSlim™ is known to be extremely
safe when used as directed.
CortiSlim™ is a dietary supplement
that is not known to negatively
interact with any medications.
However, if you have any existing
medical conditions and are taking
medication, please consult your
healthcare professional before
taking CortiSlim
Stress Management
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