Niacin-Bound Chromium Polynicotinate

Chromium Polynicotinate May Affect Body Composition (Weight Loss)

When chromium picolinate was introduced in the mid-1990s, it was heralded as another supplement to aid in weight loss, particularly by losing body fat and not lean muscle mass. In a randomised, double-blind, placebo-controlled study, 154 patients received either 200mcg/day or 400mcg/day chromium picolinate for 72 days. Both chromium groups had significantly higher positive changes in body composition compared to placebo. 1

A follow-up study by the same researchers found that those taking either 200mcg/day or 400mcg/day chromium picolinate lost significantly more weight than placebo over a 90-day period. Without any loss of fat-free mass, the chromium groups lost 7.79kg and 7.71kg vs. 1.81kg and 1.53kg for the placebo groups. 2

However, a study of 16 young men taking 200mcg/day chromium picolinate for 12 weeks showed no change in strength, lean body mass or body fat. 3 One head-to-head study pitting chromium picolinate against a newer chromium derivative, niacin-bound polynicotinate, found 400mcg/day chromium polynicotinate as used in Cortisyn, for eight weeks resulted in significant weight loss in young obese women, but no changes were seen in either the picolinate or placebo groups. Equivocal studies like these took some of the air out of the chromium picolinate balloon for its weight-loss uses (though the research was sponsored by a supplier of chromium polynicotinate).

1. Kaats G, et al. Effects of chromium picolinate supplementation on body composition: a randomized, double-masked, placebo-controlled study. Curr Therapeut Res 1996 Oct;57(10):747-56.

2. Kaats GR, et al. A randomized, double-masked, placebo-controlled study of the effects of chromium picolinate supplementation on body composition: a replication and extension of a previous study. Curr Ther Res 1998;59:379-88.

3. Hallmark MA, et al. Effects of chromium and resistive training on muscle strength and body composition. Med Sci Sports Exer 1996 Jan;28(1):139-44.

Cortisyn uses patented ChromeMate polynicotinate form.

• Helps maintain normal insulin function.
• No artificial ingredients or preservatives.
• Chromium is an essential part of the GTF (Glucose Tolerance Factor) molecule. GTF is an important cofactor for insulin in the regulation of blood sugar which is necessary for proper metabolism.
• Chromium polynicotinate meets all the requirements for GTF. It contains no artificial ingredients or preservatives.
• This product is free of common food allergens. It contains no yeast, milk, lactose, wheat, sugar or soy.