5-HTP Precautions & Side Effects

5-HTP side effects are few and is available without prescription and is generally considered safe and may be beneficial to many individuals. Contraindications to 5-HTP use or conditions under which 5-HTP use should only be under the supervision of a physician, to monitor side effects, are:

  • Cardiovascular Diseases (high blood pressure, post-stroke, post-heart attack)
  • Extremely Elderly Persons
  • Parkinsons Disease, Cancer or Autoimmune Diseases (Scleroderma, Rheumatoid Arthritis, Multiple Sclerosis, Lupus)
  • Lung Diseases
  • Chronic Alcoholism
  • Liver diseases (hepatitis or cirrhosis)
  • parasitic infection
  • AIDS
  • Anorexia Nervosa
  • Low protein Diets
  • Allergies (severe)
  • Myalgia (persistent pain and weakness of the muscles)
  • Peripheral Neuropathy (pain weakness of the muscles)
  • Rash or Flushing
  • Edema
  • Nausea
  • Diarrhea
  • Sickle cell anemia
  • hemophilia
  • Pregnancy
Concurrent drug use: 5-HTP should not be used if taking:
  • Anti-depressant drugs
  • Monoamine oxidase inhibitors
  • Selective Serotonin Reuptake Inhibitors (SSRI's e.g., Prozac)
  • Tricyclic medications
  • Weight Loss medications (i.e., dextenfluramine)
  • Anti-parkinson medications (e.g., L-dopa)
  • Barbiturates and other tranquilizing drugs
  • Antihistamines and cold medications
  • Alcoholic beverages
  • Intravenous (illegal I.V.) drugs
  • Cancer chemotherapy or
  • antibiotic medications

Alcohol and 5-HTP should not be taken together. Allow at least six hours between use of alcohol and 5-HTP.

Warning: 5-HTP can increase the effect of some tranquilizing drugs.

 

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